Medical Calculators

MELD 3.0 = 4.56 × ln(Bilirubin) + 0.82 × (137 − Na) − 0.24 × (137 − Na) × ln(Creatinine) + 9.09 × ln(INR) + 11.14 × ln(Creatinine) + 1.85 × (Female sex = 1, else 0) + 1.83 × (Albumin < 3.5) − 7

Kim et al., Hepatology 2021. Score range 6–40. Creatinine capped at 3.0 mg/dL. Na constrained to 125–137 mEq/L.

Bilirubin: <2 = 1pt, 2–3 = 2pts, >3 = 3pts  |  Albumin: >3.5 = 1pt, 2.8–3.5 = 2pts, <2.8 = 3pts  |  INR: <1.7 = 1pt, 1.7–2.2 = 2pts, >2.2 = 3pts  |  Ascites: None = 1pt, Mild = 2pts, Moderate/Severe = 3pts  |  Encephalopathy: None = 1pt, Grade I–II = 2pts, Grade III–IV = 3pts

Class A: 5–6 pts (1yr survival ~100%) · Class B: 7–9 pts (~80%) · Class C: 10–15 pts (~45%)

VOCAL-Penn Score = 0.03 × Age + 0.92 × ln(Bilirubin) + 0.70 × ln(Creatinine) + 1.17 × ln(INR) + 0.14 × ASA class − 0.30 × Albumin + 0.56 × Ascites(1=yes) + 0.97 × Emergency(1=yes)

30-day mortality risk derived from logistic regression. Higher score = higher surgical risk.

HBsAg — Hepatitis B surface antigen: present in active infection  |  Anti-HBs — Surface antibody: indicates immunity (vaccine or resolved)  |  HBeAg — e antigen: marker of high replication  |  Anti-HBe — e antibody: suggests lower replication  |  Anti-HBc IgM — Core IgM: acute infection marker  |  Anti-HBc Total — Core total: past or present infection